Control of gene expression

1.

Control of gene expression
Malyshev Nikita Vladislavovich
[email protected]
2022

2.

The Different Cell Types of a Multicellular
Organism Contain the Same DNA

3.

4.

Different Cell Types Synthesize Different Sets
of RNAs and Proteins

5.

Gene Expression Can Be Regulated at Many of the
Steps in the Pathway from DNA to RNA to Protein

6.

CONTROL OF TRANSCRIPTION BY
SEQUENCESPECIFIC DNA-BINDING PROTEINS

7.

Transcription Regulators Contain Structural Motifs
That Can Read DNA Sequences

8.

Dimerization of Transcription Regulators Increases
Their Affinity and Specificity for DNA

9.

Nucleosome Structure Promotes Cooperative
Binding of Transcription Regulators

10.

TRANSCRIPTION REGULATORS SWITCH GENES ON
AND OFF

11.

Repressors Turn Genes Off and Activators
Turn Them On

12.

An Activator and a Repressor Control the Lac
Operon

13.

A Eukaryotic Gene Control Region Consists of a Promoter Plus
Many cis-Regulatory Sequences

14.

Eukaryotic Transcription Regulators Work in Groups

15.

Eukaryotic Transcription Activators Direct the Modification of
Local Chromatin Structure

16.

Transcription Activators Can Promote Transcription by Releasing
RNA Polymerase from Promoters

17.

Transcription Activators Work Synergistically

18.

19.

The integration of multiple inputs at a promoter

20.

Combinatorial Gene Control Creates Many Different Cell Types

21.

22.

Specialized Cells Must Rapidly Turn Sets of Genes On and Off

23.

24.

Transcription Circuits Allow the Cell to Carry
Out Logic Operations