The study of adsorption-desorption interaction of amino acids with calcium phosphates. Literature review

1.

Omsk State University. F.M. Dostoevsky
Department of Inorganic Chemistry
The study of adsorption-desorption interaction of
amino acids with calcium phosphates
Golovchenko K.K.
2 year , HHM-601-O
Scientific adviser:
1
Golovanova O.A.- Professor, Doctor of
Geologo-Mineralogical Sciences Position
Professor
Omsk 2017

2.

Relevance
Calcium phosphates are part of biogenic and pathogenic mineral
formations. Interaction of organic and mineral components is
important in such processes of biogenic crystallization, as the
formation of bone matrix mammals, as well as the emergence and
growth of pathogenic entities. There are some assumptions,
according to which the basis of the processes of mineralization
lies in the adsorption interaction of free amino acids and
associated protein molecules with inorganic components of
biological liquids. In particular, such processes include
adsorption-desorption interaction. The mechanism of their
interaction is not fully understood.
In this regard, relevant studies aimed at studying the regularities
of adsorption and desorption of amino acids on calcium
phosphates.
2

3.

The purpose of this paper is to study the specific features of
the adsorption-desorption interaction of amino acids with
calcium phosphates while varying the pH of the solution.
Tasks:
The synthesis of hydroxylapatite;
Setting up an adsorption and a desorption experiments;
The study of adsorption and desorption of amino acids with
varying parameters of the initial solution.
3

4. Literature review

1.
2.
3.
4.
5.
6.
7.
8.
Adsorption
Segvich S. J., Smith H. C., Kohn D. H. 2009 The adsorption of preferential binding
peptides to apatite-based materials. Biomaterials 30, P. 1287–1298.
Zhu X. D., Zhang H. J., Fan H. S., Li W., Zhang X. D. 2009 Effect of phase composition
and microstructure of calcium phosphate ceramic particles on protein adsorption. Acta
Biomater. 6, P. 1536–1541.
Dos Santos E., Farina M., Soares G., Anselme K. 2008 Surface energy of hydroxyapatite
and β-tricalcium phosphate ceramics driving serum protein adsorption and osteoblast
adhesion. J. Mater. Sci. Mater. Med. 19, P. 2307–2316.
Zhu X. D., Fan H. S., Xiao Y. M., Li D. X., Zhang H. J., Luxbacher T., Zhang X. D. 2009
Effect of surface structure on protein adsorption to biphasic calcium-phosphate ceramics
in vitro and in vivo. Acta Biomater. 5, P. 1311–1318.
Zhu X. D., Zhang H. J., Fan H. S., Li W., Zhang X. D. 2010 Effect of phase composition
and microstructure of calcium phosphate ceramic particles on protein adsorption. Acta
Biomater. 6, P. 1536–1541.
Zhu X. D., Fan H. S., Zhao C. Y., Lu J., Ikoma T., Tanaka J., Zhang X. D. 2007
Competitive adsorption of bovine serum albumin and lysozyme on characterized calcium
phosphates by polyacrylamide gel electrophoresis method. J. Mater. Sci. Mater. Med. 18,
P. 2243–2249.
Shen J. W., Wu T., Wang Q., Pan H. H. 2008 Molecular simulation of protein adsorption
and desorption on hydroxyapatite surfaces. Biomaterials 29, P. 513–532.
Yang Y., Cui Q. A., Sahai N. 2010 How does bone sialoprotein promote the nucleation of
hydroxyapatite? A molecular dynamics study using model peptides of different
conformations. Langmuir 26, P. 9848–9859.
4

5.

9.
Pan H., Tao J., Xu X., Tang R. 2007 Adsorption processes of Gly and Glu amino acids on
hydroxyapatite surfaces at the atomic level. Langmuir 23, P. 8972–8981.
10.
Brooks B. R., et al. 2009 CHARMM: the biomolecular simulation program.
Comput. Chem. 30, P. 1545–1614.
11.
Kang Y., Li X., Tu Y., Wang Q., Agren H. 2010 On the Mechanism of Protein Adsorption
onto Hydroxylated and Nonhydroxylated TiO2 Surfaces. J. Phys. Chem. C. 114, P. 14
496–14 502.
12.
Skelton A. A., Liang T., Walsh T. R. 2009 Interplay of sequence, conformation, and
binding at the peptide–Titania interface as mediated by water. ACS Appl. Mater. Interf. 1,
P. 1482–1491.
13.
Shen J. W., Wu T., Wang Q., Kang Y. 2008 Induced stepwise conformational change of
human serum albumin on carbon nanotube surfaces. Biomaterials 29, P. 3847–3855.
14.
Forte G., Grassi A., Marletta G. 2007 Molecular modeling of oligopeptide adsorption onto
functionalized quartz surfaces. J. Phys. Chem. B. 111, P. 11 237–11 243.
15.
Bhowmik R., Katti K. S., Katti D. 2007 Molecular dynamics simulation of
hydroxyapatite–polyacrylic acid interfaces. Polymer 48, P. 664–674.
16.
Bhowmik R., Katti K. S., Verma D., Katti D. R. 2007 Probing molecular interactions in
bone biomaterials: through molecular dynamics and Fourier transform infrared
spectroscopy. Mater. Sci. Eng. C 27, P. 352–371.
J.
5

6.

17.
18.
19.
20.
de Leeuw N. H., Rabone J. A. L. 2007 Molecular dynamics
simulations of the interaction of citric acid with the hydroxyapatite
(0001) and (011−0) surfaces in an aqueous environment Cryst.
Eng. Commun. 9. P. 1178-1186
Rimola A., Corno M., Zicovich-Wilson C., Ugliengo P. 2008 Abinitio modelling of protein/biomaterial interactions: glycine
adsorption at hydroxyapatite surfaces J. Am. Chem. Soc 130. P.
16181-16183.
Rimola A., Corno M., Zicovich-Wilson C. M., Ugliengo P. 2009
Ab initio modeling of protein/biomaterial interactions: competitive
adsorption between glycine and water onto hydroxyapatite
surfaces Phys. Chem. Chem. Phys 11. P. 9005-9007.
Almora-Barrios N., Austen K. F., de Leeuw N. H. 2009 Density
functional theory study of the binding of glycine, proline, and
hydroxyproline to the hydroxyapatite (0001) and (010) surfaces
Langmuir 25. P. 5018-5025.
6

7.

1.
2.
3.
4.
Crystal chemistry of calcium phosphates
Silva G. A., Coutinho O. P., Ducheyne P., Reis R. L. 2007 Materials
in particulate form for tissue engineering. II. Applications in bone. J.
Regen. Med. V. 1. P. 97–106.
Desorption of amino acids
Xiuli Dong, Qi Wang, Tao Wu, and Haihua Pan. Understanding
Adsorption-Desorption Dynamics of BMP-2 on Hydroxyapatite
(001) Surface. Department of Chemistry, Zhejiang University,
Hangzhou, China. Biophysical Journal. V. 93 August 2007. Р. 750–
759.
Chen, X., Q. Wang, J. Shen, H. Pan, and T. Wu. 2007. Adsorption
of LRAP on hydroxyapatite (001) surface through –COO claws. J.
Phys. Chem. C. 111. Р. 1284–1290.
Huimin Wang ; Guihua Nie ; Kui Fu. Cellular Automata Model of
Protein Adsorption on the Surface of Bioceramics. 2008. P. 417420. (DOI: 10.1109/ICNC.2008.611)
Chie Kojima,Kenji Watanabe. Adsorption and Desorption of
Bioactive Proteins on Hydroxyapatite for Protein Delivery
Systems. J Drug Deliv. 2012. P. 932461.
(doi: 10.1155/2012/932461)
7