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Tissue as a system of cells and their derivatives. Epithelial tissue
1.
2.
is a complex assemblage of cells andcell derivatives, that have a common
origin, structure and functions.
3.
- Cells- Extracellular matrix
- Postcellular structures
- Symplastos: there is a common cytoplasm
and many nuclei (myosymplast,
syncytiotrophoblast)
- Sincytium: there are cytoplasmic bridges
between neighboring cells(developing male sex
cells).
4.
Myosymplast (skeletal musclefiber)
Syncytium (developing
male sex cells)
5.
Laws of evolutionary development oftissues are extended in the theory of
divergent development of
tissues(N.G.Khlopin) and the theory of
collateral series, or parallel development
of tissues (A.A.Zavarzin)
6.
considers evolutionary transformations oftissues and organisms as a divergent
process, during which each embryonic
rudiment gives rise to tissues that
gradually acquire more and more
pronounced differences in structural and
functional characteristics.
7.
is based on the similarity of the structureof tissues that perform the same
functions in unrelated groups of animals
that are far from each other in
phylogenetic terms.
8.
Similar structures in various branches ofphylogenetic tree arose parallel during
divergent development.
Tissues development (histogenesis)
occurs with processes of determination
and differentiation of their cells.
9.
Determination is the process of“programming” of the direction of their
development.
Differentiation is a process during which
of the definite tissue incomplement
potencies anchored with determination.
10.
- Is the complex of all cells of definiteline of differentiation from the least
differentiated (stem cell) up to the
most mature differentiated.
11.
There are origin of other cellsdevelopment in all types of tissues.
Properties of SC :
form self-maintained population
divides seldom
stable for damage
pluripotetial in some tissues.
12.
13.
Physiologic regenaration -is process ofrenovation during normal development of
tissue.
Reparative regenaration - is process of
tissue reconstruction after injury.
Levels of regenaration:
intracellular, cellular, tissue and organic.
14.
EpithelialMuscle
Tissues of internal medium
(connective tissue, blood and lymph)
Nervous
15.
muscularepithelial
blood
connective
nervous
16.
Еpithelialtissue
is the whole complex of differons
of differentiated cells close as a layer
on a basal membrane on border with
external or internal environment, and
also forming a majority of body
glands.
17.
18.
Еpithelialtissue:
1) covers body surface and lines
mucous and serous layers of
internal organs
(covering and lining superficial
epithelium);
2) forms parenchyma of
numerous glands
(glandular epithelium).
19.
Superficialepithelium
Glandular
epithelium
20.
Superficialepithelium
Glandular
epithelium
21.
1. Form barriers and divide the bodyinto functional compartments.
2.Protection from mechanical, physical
and chemical influences.
3. Transport of substances through
epithelium.
4.Absorbtion of substances.
5.Secretory function (in glands).
6.Sensory function (in organs of touch
taste, hearing and equilibrium).
22.
I.Simple epithelium:1. Squamous
2. Cuboidal
3. Columnar
4. Pseudostratified columnar
23.
II. Stratified epithelium :1. Stratified squamous
а) keratinized
б) nonkeratinized
2. Stratified cuboidal
3. Stratified columnar
4. Transitional
24.
1. Epidermal type (from ectoderm: skinepidermis, E of cornea, oral cavity and etc).
2. Endodermal type (from endoderm: E of
stomach, intesting and etc).
3. Coelonephrodermal (from mesoderm: E of
kidney, gonads and serous layers)
4. Ependymoglial (from neural tube: ependymal
glial cells in CNS).
5. Angiodermal (from mesenchyme: E of inner
layer of heart and vessels).
25.
Disposedon basement membrane
Form layers
Minimum of extracellular matrix or
absence of it
Epithelial cells united with junctional
complexes (lateral specializations)
26.
Polarity of epithelial cells:in columnar cells: nuclei in basal
portion, apical specializations
(microvilli, cilia, stereocilia) – in
apical portion.
Nucleus
Lack of blood and lymph vessels
High ability for regeneration
Maintenance of numerous nervous
receptors
27.
28.
All cells are on a basal membraneAccording to a shape of cells it was
distinquished:
squamous, cuboidal and columnar
epithelium.
29.
А) mesothelium –lines serous layers
30.
31.
32.
In kidney tubulesand thyroid follicles
33.
III. Simple columnarepithrlium
Cells have polarity
Epithelium lines :
- stomach,
- intestine,
- large ducts of glands.
In intestine this epithelium
has brush border.
34.
Inepithelium of
small intestine:
- Goblet cells
- surface
absorbtive cells
35.
36.
37.
38.
Pseudotratified columnar ciliatedepithelium lines mucosa of :
- respiratory tract
- some portions of male
reproductive tract
39.
Consists of several layers of epithelial cellsOnly proximal layer of cells is on a basal
lamina, others lose junctions with it.
There are different shapes of cells in
distinctive layers.
Type of epithelium estimated according
to shapes of a superficial cells layer.
40.
Stratified epithelia subdivides into:I.
Keratinized
II.
Nonkeratinized
I. Stratified squamous keratinized
epithelium is found in the skin
epidermis, mucosa of gingiva, hard
palate, filiform papilla of tonque and
skin zone of anal canal.
It forms a specialized barrier against
physical, chemical and antigens
influences.
41.
Forms outer layer of skin– epidermis.- Consists of 5 layers:
stratum basale
stratum spinosum
stratum granulosum
stratum lucidum
stratum corneum
-
42.
Stratumlucidum
43.
Covers cornea of eye, mucosaof oral cavity and pharynx,
esophagus, vagina, vaginal
portions of uterus neck.
44.
Consists of 3 layers:stratum basale
stratum spinosum
superficial layer
-
45.
Superficia l layerStratum spinosum
Stratum basale
46.
It is specialized type of epithelium, whichlines urinary tracts.
Thickness of epithelial cells in superficial
layer dependents of degree of tension of
organ.
Layers of epithelium:
basal layer
intermediate
superficial layer
47.
Superficial layerIntermediate layer
Basal layer
48.
perform the secretory function:produce and release secretory
products, provided for different
functions of organism.
49.
I.Endocrine glands
1) Produce hormones -high active
regulatory biologic substances,
circulated in blood.
2) There are ductless.
For example: thyroid, parathyroid,
suprarenal gland.
50.
Produce secretory products, which release ona surface of body (sweat, sebaceous, mammary
glands) or into cavities of organism (gastric,
intestinal, salivary glands; exocrine portion of
pancreas).
51.
1.Duct portion
2. Terminal
secretory portion
52.
TubularAlveolar
Tubulo-alveolar
1) According to shape of secretory portions
glands are subdivided into:
Tubular, alveolar and tubulo-alveolar
53.
2) According to structure of secretoryportions :
1. branched
2. unbranched
3) According to structure of duct portions:
1. simple (with unbranched duct)
2. compound (with branched duct)
54.
Simple tubularbranched
Simple tubular
unbranched
Simple alveolar
unbranched
Simple alveolar
branched
Compound
branched alveolar
Compound branched
tubulo-alveolar
Endocrine glands
55.
1) Mucous2)Serous
3) Mixed (serous-mucous)
4) Sebaceous
5) Saline (sweat)
56.
1) merocrine (secretion byexocytosis)
2) apocrine (secretion with
destruction of apical portion of cell)
3) holocrine (secretion with total
destruction of cell)