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Control of gene expression
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Control of gene expressionMalyshev Nikita Vladislavovich
[email protected]
2022
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The Different Cell Types of a MulticellularOrganism Contain the Same DNA
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Different Cell Types Synthesize Different Setsof RNAs and Proteins
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Gene Expression Can Be Regulated at Many of theSteps in the Pathway from DNA to RNA to Protein
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CONTROL OF TRANSCRIPTION BYSEQUENCESPECIFIC DNA-BINDING PROTEINS
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Transcription Regulators Contain Structural MotifsThat Can Read DNA Sequences
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Dimerization of Transcription Regulators IncreasesTheir Affinity and Specificity for DNA
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Nucleosome Structure Promotes CooperativeBinding of Transcription Regulators
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TRANSCRIPTION REGULATORS SWITCH GENES ONAND OFF
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Repressors Turn Genes Off and ActivatorsTurn Them On
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An Activator and a Repressor Control the LacOperon
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A Eukaryotic Gene Control Region Consists of a Promoter PlusMany cis-Regulatory Sequences
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Eukaryotic Transcription Regulators Work in Groups15.
Eukaryotic Transcription Activators Direct the Modification ofLocal Chromatin Structure
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Transcription Activators Can Promote Transcription by ReleasingRNA Polymerase from Promoters
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Transcription Activators Work Synergistically18.
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The integration of multiple inputs at a promoter20.
Combinatorial Gene Control Creates Many Different Cell Types21.
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Specialized Cells Must Rapidly Turn Sets of Genes On and Off23.
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Transcription Circuits Allow the Cell to CarryOut Logic Operations