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Respiratory system
1. Module: Respiratory system
• Topic : Destructive pulmonary diseases. Morphologicalcharacteristics, outcomes and complications. Causes of
death. Causes of death. Peculiarities in children.
• Compiled by d.m.s. Shabdarbaeva D.М.
.
2. The aim of lesson :
• Learn how to determine the morphologicalcharacteristics of lung destructive diseases (Abscesses,
gangrene) explain the causes, mechanism of
development and outcomes. To be able to assess the
significance of potential complications. To study the
pathogenesis and morphological characteristics of lung
abscess and gangrene, peculiarities in children.
Correlate morphology with clinical manifestations,
possible complications and causes of death.
3. The objectives :
• Student must know :• Morphological characteristics of pulmonary destructive diseases,
gangrene, chronic abscess;
• Age peculiarities;
• Correlate morphology with clinical manifestations, possible
complications and causes of death
• Student must be able :
• how to determine the morphological characteristics of lung destructive
diseases (Abscesses, gangrene) explain the causes, mechanism of
development and outcomes. To be able to assess the significance of
potential complications.
4. Lung abscess
5. lung abscess
6.
7. lung abscess
8. lung abscess
9.
Upper lobePleura
Abscess
Fibrous tissue
Middle lobe
Lower lobe
10.
Gangrene11. lung abscess
12.
Lung gangrenePurulent putrid
necrosis
Lungs
13. Lung tissue with asbestosis
АВ
А-fibrosis of interalveolar walls, В-unaltered inter alveolar septa.
14. Lymph nodes in sarcoidosis
АВ
А - noncaseous granuloma, В-giant cell.
15. Lungs, polypoid tumor
ВА
А-polypoid tumor В-segmental bronchus.
16. Lungs, peripheral adenocarcinoma
АВ
А-papillary outgrowths, В-fibrovascular trunk
17. Large-cell lung cancer
АВ
А-giant cells, В – focal necrosis.
18. Material of bronchoscopy in lung cancer
ВА-infiltrative tumor, В-epithelium.
А
19. Lymph Node biopsy
АВ
А-mitosis, В-apoptosis
20. A bone marrow biopsy (metastases)
ВА
С
А-bone tissue lysis, В- merger of nuclei, С- scanty cytoplasm