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Pathogens of atypical pneumonia
1.
PATHOGENS OF ATYPICALPNEUMONIA
Upasana Saxena
3 rd year, group 312
Scientific supervisors PhD, associate Professor L.M. Aznabaeva
Department of Microbiology, Virology, Immunology,
Orenburg state medical university
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AIM –The goal is to learn about SARS-COV viruses (SARS-COV,
MERSCOV, SARS-COV-2), features of pathogenesis, causes,
prevalence in India.
Materials and methodsAnalysis of world literature data on the prevalence of SARS
in the world, the taxonomy of pathogens, analysis of data
from various institutions
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3.
INTRODUCTIONInfectious SARS, also known as severe acute respiratory
syndrome (SARS), is an acute respiratory infectious disease
caused by the SARScoronavirus (SARS-CoV). Clinically, it is
characterized by fever, headache, muscle soreness, fatigue,
dry cough, rarely with sputum, and diarrhea. Most patients
have concomitant pneumonia. In severe cases, these
conditions can develop into acute lung injury, acute
respiratory distress syndrome (ARDS), or even multiple
organ failure, which leads to death.
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Prevalence in indiaThe current estimate of mortality from infection is 0.5-1%. Using modern models of
infection mortality rates depending on age, the upper and lower limits of infection
rates in Germany can be estimated in the range from 0.4 to 1.6%, which is lower
than in most European countries SARS-CoV-2 is a newly emerged coronavirus.
Infections in humans were first detected in late 2019 in Wuhan, China. In the
following months, the virus spread rapidly around the world. SARS-CoV-2
reproduces mainly in the upper and lower respiratory tract and is highly infectious.
Droplets and aerosol are the main transmission routes, and infection also occurs
through asymptomatic infected individuals. Almost 90% of cases proceed without
complications, in a minority of cases severe diseases and complications occur. Risk
factors for the development of severe diseases are old age, hypertension, diabetes
mellitus, chronic heart or lung diseases and immunodeficiency.
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Epidemiogical data8.
Explaination of figure ( epidemiogical data)• characteristics of SARS-CoV-2, SARS-CoV, MERS-CoV, and influenza
A viruses. (A) Epidemics of SARS-CoV-2, SARS-CoV, MERS-CoV, and
influenza A viruses. The timeline, natural reservoirs, total number
of deaths, and symptoms of the patients infected with these
viruses. (B) Cumulative numbers of cases and deaths caused by
SARS-CoV-2, SARS-CoV, MERS-CoV, and influenza A (during the last
seasonal flu 2019–2020) viruses. Influenza A virus infected the
most people, while SARS-CoV-2 caused the most deaths. (C) Casefatality rate (CFR) of patients infected with SARS-CoV-2, SARSCoV, MERS-CoV, and influenza A (the last seasonal flu 2019–2020)
viruses stratified by age.
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CONCLUSIONDespite the appearance of a completely newvirus and the atypical nature of the disease,
the medical community was able to develop
timely methods for identifying the pathogen,
treatment aimed at preventing or minimizing
complications, as well as a vaccine against
the new SARS virus.
10.
ACKNOWLEDGEMENTI am thankful to my teacher AZNABAEVA LILIYA MIDEKHATEAVNA (Scientificsupervisors PhD, associate Professor ), Department of Microbiology, Virology,
Immunology] for giving me an opportunity to present my thesis on
PATHOGENES OF ATYPICAL PNEUMONIA- SARS COV, MERS-COV, SARS COV 2
to the scientific society.
I also give thanks to the Department of microbiology OrGMU for engaging
students of foreign faculty in these activities in order to increase the
exposure of their hidden ideas to the front. This has given a native student
like me a chance to bring about the latest updates about the disease in our
country and measures taken up by them